Research Journal of Pharmacognosy and Phytochemistry

Umesh Dhaked ¹, Gaurav Nama ², Devendra P. Singh ³, Amit K. Mishra ³, Nitin Kumar ³

Affiliations
1 School of Pharmaceutical Sciences, Jaipur National University, Jaipur- 302025, (Raj), IN
2 School of Pharmaceutical Sciences, Jaipur National University, Jaipur-302025, (Raj), IN
3 Bhagwant Institute of Pharmacy, Muzaffarnagar (U.P.), IN

Abstract

Barleria prionitis Root or Vajradanti is a herb used in cure of various ailments traditionally. Barleria prionitis Root or Vajradanti is used locally on skin to expel out spine from the skin, in acute stages of cyst in blood vessels, in glandular swellings, as diuretic, rich in potassium salts and in bronchial asthma etc. Pharmacologically, Barleria prionitis Root or Vajradanti possesses Antifertility effects, Antiarthritic activity, Inhibitory activity against glutathione S-transferase. (GST) and acetyl cholinesterase (AChE) inhibitory activity, Antiviral activity.

Keywords

Barleria prionitis Root, Pharmacological Activities, Traditional Uses.

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Nitin Kumar ¹, Satyendra Singh ¹, Manvi ¹, Rajiv Gupta ¹

Affiliations
1 Department of Pharmacognosy, Babu Banarasi Das National Institute of Technology and Management, Dr. Akhilesh Das Nagar, Faizabad Road, Lucknow 227 105 U.P, IN

Abstract

Trichosanthes dioica R. (Cucurbitaceae), an important perennial herb found throughout the Asia and is figured high in Indian medicine system for its versatile therapeutic and prophylactic properties. To justify its traditional claim, hair growth activity was performed with ethanol and aqueous extracts on wistar albino rats using minoxidil as standard. The extracts were formulated as 5% ointments and formulations were applied topically on the denuded back of rats. Both formulations exhibited prominent hair growth activity as compared to control group (p<0.05) as well as minoxidil treated group. The number of hairs and hair length were also measured which were more significant for formulations. Formulation having 5% aqueous extract found more potent than other groups. The results of this study revealed the presence of strong hair growth potential in the leaves of Trichosanthes dioica R.

Keywords

Alopecia, Minoxidil, Ointment, Hair Growth.

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